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The table below summarizes other drug features of both tizanidine and cyclobenzaprine.

Do not take more than three doses36 mgof tizanidine in a 24-hour periodToo much of tizanidine can damage your liverCold or allergy medicinenarcotic pain medicinesleeping pillsother muscle relaxersand medicine for seizuresdepression or anxiety can add to sleepiness caused by tizanidineTell your doctor if you need to use any of these other medicines together with Zanaflex.

Concomitant ciprofloxacin or fluvoxamineor other potent CYP1A2 inhibitors.

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