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Information about Prednisone.

12 yearsacute40 mg orally every 12 hoursmaintenance40 mg orally every other day.

Prednisone is a corticosteroidIt prevents the release of substances in the body that cause inflammationIt also suppresses the immune system.

The maximal activity of the adrenal cortex is between 2 am and 8 amand it is minimal between 4 pm and midnightExogenous corticosteroids suppress adrenocorticoid activity the least when given at the time of maximal activityamfor single dose administrationThereforeit is recommended that prednisone be administered in the morning prior to 9 am and when large doses are givenadministration of antacids between meals to help prevent peptic ulcersMultiple dose therapy should be evenly distributed in evenly spaced intervals throughout the day.

Prednisone treats many different conditions such as allergic disordersskin conditionsulcerative colitisarthritislupuspsoriasisor breathing disorders.

Sulfonylureas such as glipizide or glyburide biguanides such as metformin thiazolidinediones such as pioglitazone or rosiglitazone acarbose metiglinides such as nateglinide or repaglinide.

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